If I choose the option to support Sons of Anu the game continues as normal.
If I choose the option to support Synedron instead, the game freezes up on me. The “OK” button is displayed and you can click it…nothing happens.
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I’ve had something similar asked to support slaughtering the unbelievers/unevolved (or words to that effect) after fending of an attack on one of their colonies. Screen pops up with a chubby blue hooded head and titled ‘6th Initiation’ asking me to join them. I take the “no it’s barbaric” option, the screen swaps out to tell me what I recovered from the combat, pops back to the blue head with the huge OK button that does nothing.
At first I thought, well, that’s awfully polite…
Thought I’d mention, when this happens PP isn’t idle. task manager tells me it’s using about 12% CPU.
Also, I go back to the same position and repeat the same thing if I kill PP & continue on restart. Can upload autosave if you tell me where…
A fairly hard failure. Went back to an earlier save and repeated the mission. Still locks up at the same place when I refuse the Anu request. It appears to be impassible.
If you choose the other option you can continue the game…but like you, I DON’T WANT to choose the other option.
Already thrown this one into the pot
@Whiterlight we learned it by clicking “no” and having our games freezing on us! 
Thankfully, even if you carry out the mission, the haven still lives and any relations with Synedrion still stands.